Show Reference: "Interaction of Cortex and Superior Colliculus in Mediation of Visually Guided Behavior in the Cat"

Interaction of Cortex and Superior Colliculus in Mediation of Visually Guided Behavior in the Cat Science, Vol. 153, No. 3743. (23 September 1966), pp. 1544-1547 by James M. Sprague
@article{sprague-1966,
    abstract = {Total contralateral hemianopia follows unilateral removal of the entire occipito-temporal neocortex in the cat. This deficit is classically ascribed to interruption of visual radiations serving cortical function ("cortical blindness") and is considered permanent. Return of vision to the hemianopic field after subsequent removal of the superior colliculus contralateral to the cortical lesion demonstrates that neither assumption is correct. The initial hemianopia is apparently due to depression of function of the colliculus ipsilateral to the cortical lesion, a de- pression maintained by influx of inhibition from the crossed colliculus. Thus, removal of the contralateral tectum, or splitting of the collicular commissure, abolishes this inhibition and allows the return of function in the ipsilateral colliculus, and with it the recovery fronm hemianopia. These findings emphasize that visually guided behavior is mediated at both cortical and midbrain levels, and that there is a marked interaction between these sites.},
    author = {Sprague, James M.},
    day = {23},
    issn = {0036-8075},
    journal = {Science},
    keywords = {biology, consciousness, sc, visual, visual-processing},
    month = sep,
    number = {3743},
    pages = {1544--1547},
    pmid = {5917786},
    posted-at = {2013-12-05 15:38:26},
    priority = {2},
    publisher = {American Association for the Advancement of Science},
    title = {Interaction of Cortex and Superior Colliculus in Mediation of Visually Guided Behavior in the Cat},
    url = {http://view.ncbi.nlm.nih.gov/pubmed/5917786},
    volume = {153},
    year = {1966}
}

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In the Sprague effect, removing (or deactivating) one visual cortex eliminates visually induced orienting behavior to stimuli in the contralateral hemifield.

Lesioning (or deactivating) the contralateral SC restores the orienting behavior.

``The heminanopia that follows unilateral removal of the cortex that mediates visual behavior cannot be explained simply in classical terms of interruption of the visual behavior cannot be explained simply in classical terms of interruption of the visual radiations that serve cortical function.
Explanation fo the deficit requires a broader point of view, namely, that visual attention and perception are mediated at both forebrain and midbrain levels, which interact in their control of visually guided behavior.''

(Sprague, 1966)