Show Reference: "Impulse Activity and the Patterning of Connections During CNS Development"

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Retinal waves of spontaneous activity in the retina occur before photoreceptors develop.

They are thought to be involved in setting up the spatial organization of the visual pathway.

LGN and V4 have distinct layers for each eye.

The distinct layers for each eye in LGN and V4 only arise after the initial projections from the retina are made, but, in higher mammals, before birth.

Most neurons in the visual cortex (except v4) are binocular.

Usually, input from one eye is dominant, however.

The distribution of monocular dominance in visual cortex neurons is drastically affected by monocular stimulus deprivation during early development.

Competition appears to be a major factor in organizing the visual system.