Show Reference: "Single-Unit Responses Selective for Whole Faces in the Human Amygdala"

Single-Unit Responses Selective for Whole Faces in the Human Amygdala Current Biology, Vol. 21, No. 19. (11 October 2011), pp. 1654-1660, doi:10.1016/j.cub.2011.08.035 by Ueli Rutishauser, Oana Tudusciuc, Dirk Neumann, et al.
    abstract = {The human amygdala is critical for social cognition from faces, as borne out by impairments in recognizing facial emotion following amygdala lesions [1] and differential activation of the amygdala by faces [25]. Single-unit recordings in the primate amygdala have documented responses selective for faces, their identity, or emotional expression [6, 7], yet how the amygdala represents face information remains unknown. Does it encode specific features of faces that are particularly critical for recognizing emotions (such as the eyes), or does it encode the whole face, a level of representation that might be the proximal substrate for subsequent social cognition? We investigated this question by recording from over 200 single neurons in the amygdalae of seven neurosurgical patients with implanted depth electrodes [8]. We found that approximately half of all neurons responded to faces or parts of faces. Approximately 20\% of all neurons responded selectively only to the whole face. Although responding most to whole faces, these neurons paradoxically responded more when only a small part of the face was shown compared to when almost the entire face was shown. We suggest that the human amygdala plays a predominant role in representing global information about faces, possibly achieved through inhibition between individual facial features. º About 50\% of the neurons in the human amygdala responded to faces or parts thereof º About 20\% of amygdala neurons responded best to the presentation of whole faces º Their response to face parts was not predictive of the response to the whole face º Whole-face-selective units are candidates for holistic face perception},
    author = {Rutishauser, Ueli and Tudusciuc, Oana and Neumann, Dirk and Mamelak, Adam N. and Heller, A. Christopher and Ross, Ian B. and Philpott, Linda and Sutherling, William W. and Adolphs, Ralph},
    day = {11},
    doi = {10.1016/j.cub.2011.08.035},
    issn = {09609822},
    journal = {Current Biology},
    keywords = {amygdala},
    month = oct,
    number = {19},
    pages = {1654--1660},
    posted-at = {2013-04-08 09:55:15},
    priority = {2},
    publisher = {Cell Press},
    title = {{Single-Unit} Responses Selective for Whole Faces in the Human Amygdala},
    url = {},
    volume = {21},
    year = {2011}

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Cells in the amygdala respond to faces and parts of faces. Some react exclusively to faces.