# Show Reference: "Monkey Dorsolateral Prefrontal Cortex Sends Task-Selective Signals Directly to the Superior Colliculus"

Monkey Dorsolateral Prefrontal Cortex Sends Task-Selective Signals Directly to the Superior Colliculus The Journal of Neuroscience, Vol. 26, No. 48. (29 November 2006), pp. 12471-12478, doi:10.1523/jneurosci.4101-06.2006 by Kevin Johnston, Stefan Everling
@article{johnston-and-everling-2006,
abstract = {The dorsolateral prefrontal cortex ({DLPFC}) has been implicated in the ability to perform complex behaviors requiring the implementation of cognitive control. A central supposition of models of prefrontal function is that the {DLPFC} engages control by selectively modulating the activity of target structures to which it is connected, but no studies in the primate have directly investigated {DLPFC} output signals. Here, we recorded the activity of {DLPFC} neurons identified as sending a direct projection to the superior colliculus, a midbrain oculomotor structure, while monkeys performed alternating blocks of trials in which they had to look toward a flashed peripheral stimulus (prosaccades) and trials in which they had to look away from the stimulus in the opposite direction (antisaccades). We report the first direct evidence that the primate {DLPFC} sends task-selective signals to a target structure. This supports the notion that the {DLPFC} orchestrates the activity of other brain areas in accordance with task requirements.},
author = {Johnston, Kevin and Everling, Stefan},
citeulike-article-id = {9791125},
day = {29},
doi = {10\%2e1523/jneurosci\%2e4101\%2d06\%2e2006},
issn = {1529-2401},
journal = {The Journal of Neuroscience},
keywords = {biology, cortex, dlpfc, sc, sc-connectivity, sc-input},
month = nov,
number = {48},
pages = {12471--12478},
pmid = {17135409},
posted-at = {2015-01-15 15:17:49},
priority = {2},
title = {Monkey Dorsolateral Prefrontal Cortex Sends {Task-Selective} Signals Directly to the Superior Colliculus},
url = {http://dx.doi.org/10\%2e1523/jneurosci\%2e4101\%2d06\%2e2006},
volume = {26},
year = {2006}
}