Show Reference: "Multiple Sites of Adaptive Plasticity in the Owl's Auditory Localization Pathway"

@article{debello-and-knudsen-2004,
    abstract = {In the midbrain auditory localization pathway of the barn owl, a map of auditory space is relayed from the external nucleus of the inferior colliculus ({ICX}) to the deep and intermediate layers of the optic tectum ({OT}) and from these layers to the superficial layers. Within the {OT}, the auditory space map aligns with a visual map of space. Raising young barn owls with a prismatic displacement of the visual field leads to progressive changes in auditory tuning in the {OT} that tend to realign the auditory space map with the prismatically displaced visual space map. The only known site of this adaptive plasticity is in the {ICX}, in which the auditory system first creates a map of space. In this study, we identified an additional site of plasticity in the {OT}. In owls that experienced prisms beginning late in the juvenile period, adaptive shifts in auditory tuning in the superficial layers of the {OT} exceeded the adaptive shifts that occurred in the deep layers of the {OT} or in the {ICX}. Anatomical results from these owls demonstrated that the topography of intrinsic {OT} connections was systematically altered in the adaptive direction. In juvenile owls, plasticity in the {OT} increased as plasticity in the {ICX} decreased. Because plasticity at both sites has been shown to decline substantially in adults, these results suggest that an age-dependent decrease in auditory map plasticity occurs first in the {ICX} and later at the higher level, in the {OT}.},
    author = {DeBello, William M. and Knudsen, Eric I.},
    day = {04},
    doi = {10.1523/jneurosci.0480-04.2004},
    issn = {1529-2401},
    journal = {The Journal of Neuroscience},
    keywords = {auditory, auditory-processing, biology, ic, icx, ssl, topographic-maps},
    month = aug,
    number = {31},
    pages = {6853--6861},
    pmid = {15295019},
    posted-at = {2013-11-07 11:23:09},
    priority = {2},
    publisher = {Society for Neuroscience},
    title = {Multiple Sites of Adaptive Plasticity in the Owl's Auditory Localization Pathway},
    url = {http://dx.doi.org/10.1523/jneurosci.0480-04.2004},
    volume = {24},
    year = {2004}
}