Show Reference: "Functional Identification of a Pulvinar Path from Superior Colliculus to MT"

Functional Identification of a Pulvinar Path from Superior Colliculus to MT The Journal of Neuroscience, Vol. 30, No. 18. (5 May 2010), pp. 6342-6354, doi:10.1523/jneurosci.6176-09.2010 by Rebecca A. Berman, Robert H. Wurtz
@article{berman-and-wurtz-2010,
    abstract = {The idea of a second visual pathway, in which visual signals travel from brainstem to cortex via the pulvinar thalamus, has had considerable influence as an alternative to the primary geniculo-striate pathway. Existence of this second pathway in primates, however, is not well established. A major question centers on whether the pulvinar acts as a relay, particularly in the path from the superior colliculus ({SC}) to the motion area in middle temporal cortex ({MT}). We used physiological microstimulation to identify pulvinar neurons belonging to the path from {SC} to {MT} in the macaque. We made three salient observations. First, we identified many neurons in the visual pulvinar that received input from {SC} or projected to {MT}, as well as a largely separate set of neurons that received input from {MT}. Second, and more importantly, we identified a subset of neurons as relay neurons that both received {SC} input and projected to {MT}. The identification of these relay neurons demonstrates a continuous functional path from {SC} to {MT} through the pulvinar in primates. Third, we histologically localized a subset of {SC}-{MT} relay neurons to the subdivision of inferior pulvinar known to project densely to {MT} but also localized {SC}-{MT} relay neurons to an adjacent subdivision. This pattern indicates that the pulvinar pathway is not limited to a single anatomically defined region. These findings bring new perspective to the functional organization of the pulvinar and its role in conveying signals to the cerebral cortex.},
    author = {Berman, Rebecca A. and Wurtz, Robert H.},
    day = {5},
    doi = {10.1523/jneurosci.6176-09.2010},
    issn = {1529-2401},
    journal = {The Journal of Neuroscience},
    keywords = {biology, sc, sc-output},
    month = may,
    number = {18},
    pages = {6342--6354},
    pmcid = {PMC2919315},
    pmid = {20445060},
    posted-at = {2013-03-05 09:53:30},
    priority = {2},
    title = {Functional Identification of a Pulvinar Path from Superior
Colliculus to {MT}},
    url = {http://dx.doi.org/10.1523/jneurosci.6176-09.2010},
    volume = {30},
    year = {2010}
}

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There seems to be an ascending pathway from superficial SC to the medial temporal area (MT) through the pulvinar nuclei (inferior pulvinar).

Berman and Wurtz found neurons in the pulvinar nuclei which received input from SC and sent output to MT.

Pulvinar neurons project to the SC.

Pulvinar neurons receive input from the MT.

There seem to be few, if any, neurons in the pulvinar which receive input from and project to neurons in the same region of MT.

Pulvinar neurons seem to receive input and project to different layers in visual cortex:

They receive input from layer 5 and project to layers one and three.